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Diabetes treatments: Looking Backward, Looking Forward

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The Roman God Janus, above, is the god of beginnings, gates, transitions, time, duality, doorways,[2] passages, frames, and endings. He is usually depicted as having two faces. The month of January is named for Janus (Ianuarius).

The Year’s Biggest Medical Advancements in Diabetes Treatment

Trailblazing Discoveries: The Top 5 Diabetes Research Breakthroughs of 2023

  • The evolution of insulin therapy

Over the years, there have been significant improvements in insulin formulations and modes of delivery. These include rapid-acting insulin, short-acting insulin, intermediate-acting insulin, and long-acting insulin. Each type has unique pharmacokinetics and pharmacodynamics, determining the timing and duration of its effect on blood glucose levels.

In recent years, there have been notable advancements in insulin therapy. One area of focus has been the development of insulin pumps. Additionally, research has explored novel approaches to insulin delivery, such as the use of nanomaterials for oral administration.

In 2023, there have been advancements in insulin formulations and affordability. New biosimilars have been approved, providing more affordable options for patients (e.g.  Admelog (insulin lispro), an approved biosimilar of Humalog).

  • Innovative technological advancements for diabetes management

  • Discovering the role of new genes in diabetes

  • Breakthroughs in alternative therapies

  • Towards a cure: promising research in 2023

When asked what possible advancements are on his radar for 2024, Pajvani said he’s particularly looking forward to results from trials of newer drugs for both type 2 diabetes and obesity, including oral GLP-1 receptor activators that may further expand the treatment options. He also said technology will be front and center “with new models of care developing an expansion of digital health.”


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